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Anti-CRK Monoclonal Antibody (2T349)
(Synonyms: CRKII) Copy Product Info
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Synonyms: CRKII
Catalog No. TMAT-1061 Copy Product Info
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Anti-CRK Monoclonal Antibody (2T349) is a Mouse antibody targeting CRK. Anti-CRK Monoclonal Antibody (2T349) can be used in IHC,IF,FCM.
Anti-CRK Monoclonal Antibody
(2T349)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CRK Monoclonal Antibody (2T349) is a Mouse antibody targeting CRK. Anti-CRK Monoclonal Antibody (2T349) can be used in IHC,IF,FCM. |
| Synonyms | CRKII |
| Ig Type | IgG2b |
| Clone | 2T349 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CRK expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CRK |
| Gene ID | |
| Protein Name | Adapter molecule crk |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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