5-Hydroxyferulic acid

Name: 5-Hydroxyferulic acid
Brand: TargetMol
SKU: T39198
Rating: 4.5 (1 reviews)

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Catalog No. T39198Cas No. 1782-55-4

5-Hydroxyferulic acid is an important hydroxycinnamic acid compound and a metabolite in the phenylpropanoid pathway. It acts as a precursor for the biosynthesis of sinapic acid and functions as a non-esterified substrate for COMT.

5-Hydroxyferulic acid

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Catalog No. T39198Cas No. 1782-55-4

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Product Introduction

Bioactivity

Description	5-Hydroxyferulic acid is an important hydroxycinnamic acid compound and a metabolite in the phenylpropanoid pathway. It acts as a precursor for the biosynthesis of sinapic acid and functions as a non-esterified substrate for COMT.
In vitro	The alfalfa caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase (COMT)-mediated conversion of 5-hydroxyferulic acid results in the formation of sinapic acid. The rate of 5-hydroxyferulic acid O-methyltransferase activity (pkat mg^-1 protein) in the stem material decreases in transgenic alfalfa exhibiting COMT downregulation[1].

Chemical Properties

Molecular Weight	210.185
Formula	C₁₀H₁₀O₅
Cas No.	1782-55-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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