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Anti-CD85K Monoclonal Antibody (4A304)

(Synonyms: LIR-5, LIR5, LILRB4, ILT-3, ILT3) Copy Product Info
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Synonyms: LIR-5, LIR5, LILRB4, ILT-3, ILT3

Catalog No. TMAT-0455 Copy Product Info
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Anti-CD85K Monoclonal Antibody (4A304) is a Mouse antibody targeting CD85K. Anti-CD85K Monoclonal Antibody (4A304) can be used in IHC,IF,FCM.

Anti-CD85K Monoclonal Antibody
(4A304)

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Product Introduction

Bioactivity
Description
Anti-CD85K Monoclonal Antibody (4A304) is a Mouse antibody targeting CD85K. Anti-CD85K Monoclonal Antibody (4A304) can be used in IHC,IF,FCM.
SynonymsLIR-5, LIR5, LILRB4, ILT-3, ILT3
Ig Type
IgG1
Clone
4A304
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/ml
Research BackgroundThis gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human CD85K (AA: 22-259) expressed in E. Coli.
Antigen Species
Human
Gene Name
LILRB4
Gene ID
Protein Name
Leukocyte immunoglobulin-like receptor subfamily B member 4
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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