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Anti-ALK/p80 Monoclonal Antibody (8W461)
(Synonyms: NBLST3, CD246) Copy Product Info
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Synonyms: NBLST3, CD246
Catalog No. TMAT-0064 Copy Product Info
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Anti-ALK/p80 Monoclonal Antibody (8W461) is a Mouse antibody targeting ALK/p80. Anti-ALK/p80 Monoclonal Antibody (8W461) can be used in WB,IHC,FCM.
Anti-ALK/p80 Monoclonal Antibody
(8W461)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-ALK/p80 Monoclonal Antibody (8W461) is a Mouse antibody targeting ALK/p80. Anti-ALK/p80 Monoclonal Antibody (8W461) can be used in WB,IHC,FCM. |
| Synonyms | NBLST3, CD246 |
| Ig Type | IgG1 |
| Clone | 8W461 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human ALK/p80 (AA: 1359-1460) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | ALK |
| Gene ID | |
| Protein Name | ALK tyrosine kinase receptor |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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