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Anti-SIRT3 Monoclonal Antibody (3I312)
(Synonyms: SIR2L3) Copy Product Info
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Synonyms: SIR2L3
Catalog No. TMAT-1584 Copy Product Info
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Anti-SIRT3 Monoclonal Antibody (3I312) is a Mouse antibody targeting SIRT3. Anti-SIRT3 Monoclonal Antibody (3I312) can be used in WB,FCM.
Anti-SIRT3 Monoclonal Antibody
(3I312)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Stability & Storage
| Description | Anti-SIRT3 Monoclonal Antibody (3I312) is a Mouse antibody targeting SIRT3. Anti-SIRT3 Monoclonal Antibody (3I312) can be used in WB,FCM. |
| Synonyms | SIR2L3 |
| Ig Type | IgG1 |
| Clone | 3I312 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SIRT3 (AA: 155-290) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SIRT3 |
| Gene ID | |
| Protein Name | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
| Uniprot ID |
| Molecular Weight | Theoretical: 43.6 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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