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Anti-PMAIP1 Monoclonal Antibody (8T353)
(Synonyms: NOXA, APR) Copy Product Info
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Synonyms: NOXA, APR
Catalog No. TMAT-1289 Copy Product Info
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Anti-PMAIP1 Monoclonal Antibody (8T353) is a Mouse antibody targeting PMAIP1. Anti-PMAIP1 Monoclonal Antibody (8T353) can be used in FCM.
Anti-PMAIP1 Monoclonal Antibody
(8T353)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-PMAIP1 Monoclonal Antibody (8T353) is a Mouse antibody targeting PMAIP1. Anti-PMAIP1 Monoclonal Antibody (8T353) can be used in FCM. |
| Synonyms | NOXA, APR |
| Ig Type | IgG1 |
| Clone | 8T353 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene promotes activation of caspases and apoptosis, Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human PMAIP1 (AA: 1-54) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | PMAIP1 |
| Gene ID | |
| Protein Name | Phorbol-12-myristate-13-acetate-induced protein 1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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