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9-OxoOTrE

Name: 9-OxoOTrE
Brand: TargetMol
SKU: T37868
Price: 287 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: 9-KOTrE) Copy Product Info

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Synonyms: 9-KOTrE

Catalog No. T37868 Copy Product Info

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9-OxoOTrE is a lipoxygen metabolite produced by the oxidation of 9-HpOTrE. 9-OxoOTrE exhibits antimicrobial activity against a variety of plant pathogenic microorganisms, including bacteria and fungi, and can be used in research on plant defense mechanisms and plant-pathogen interactions.

Cas No. 125559-74-2

Pack Size	Price	USA Stock	Global Stock
25 µg	$287	-	In Stock
50 µg	$548	-	In Stock
100 µg	$987	35 days	35 days
250 µg	$2,430	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Liquid

Color:Transparent

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Product Introduction

Bioactivity

Description	9-OxoOTrE is a lipoxygen metabolite produced by the oxidation of 9-HpOTrE. 9-OxoOTrE exhibits antimicrobial activity against a variety of plant pathogenic microorganisms, including bacteria and fungi, and can be used in research on plant defense mechanisms and plant-pathogen interactions.
In vitro	Method: Plant pathogenic fungi (Botrytis cinerea, Cladosporium herbarum) and oomycetes (Phytophthora parasitica, Phytophthora infestans) were pre-germinated in liquid medium for 16 h, then exposed to 9-OxoOTrE (100 μM) and incubated for an additional 24 h at 25 °C (18 °C for P. infestans). Mycelial growth inhibition was determined by microspectrophotometry (595 nm) or fluorometry (for P. infestans). Result: 9-OxoOTrE exhibited inhibition rates of 98% against C. herbarum, 97% against P. parasitica, 98% against B. cinerea, 65% against F. oxysporum, 32% against Rhizopus sp., 37% against A. brassicicola, and 98% against P. infestans ^[1].
Synonyms	9-KOTrE

Chemical Properties

Molecular Weight	292.41
Formula	C₁₈H₂₈O₃
Cas No.	125559-74-2
Smiles	C(C(/C=C/C=C\C/C=C\CC)=O)CCCCCCC(O)=O
Relative Density.	0.980 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 1 mg/mL (3.42 mM), Sonication is recommended.

Ethanol: 25 mg/mL (85.5 mM), Sonication is recommended.

DMSO: 25 mg/mL (85.5 mM), Sonication is recommended.

DMF: 25 mg/mL (85.5 mM), Sonication is recommended.

In Vivo Formulation

PBS: < 1 mg/mL (insoluble)

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

PBS (pH 7.2)/Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	3.4199 mL	17.0993 mL	34.1986 mL	170.9928 mL

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.6840 mL	3.4199 mL	6.8397 mL	34.1986 mL
10 mM	0.3420 mL	1.7099 mL	3.4199 mL	17.0993 mL
20 mM	0.1710 mL	0.8550 mL	1.7099 mL	8.5496 mL
50 mM	0.0684 mL	0.3420 mL	0.6840 mL	3.4199 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc