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Anti-WT1 Monoclonal Antibody (9B953)
(Synonyms: WT33, WIT-2, WAGR, NPHS4, GUD, AWT1) Copy Product Info
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Synonyms: WT33, WIT-2, WAGR, NPHS4, GUD, AWT1
Catalog No. TMAT-0892 Copy Product Info
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Anti-WT1 Monoclonal Antibody (9B953) is a Mouse antibody targeting WT1. Anti-WT1 Monoclonal Antibody (9B953) can be used in WB,IHC,IF,FCM.
Anti-WT1 Monoclonal Antibody
(9B953)
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Product Introduction
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| Description | Anti-WT1 Monoclonal Antibody (9B953) is a Mouse antibody targeting WT1. Anti-WT1 Monoclonal Antibody (9B953) can be used in WB,IHC,IF,FCM. |
| Synonyms | WT33, WIT-2, WAGR, NPHS4, GUD, AWT1 |
| Ig Type | IgG1 |
| Clone | 9B953 |
| Reactivity | Human,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human WT1 (AA: 1-181) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | WT1 |
| Gene ID | |
| Protein Name | Wilms tumor protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 49.2 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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