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Anti-DNMT3A Monoclonal Antibody (4U476)

(Synonyms: TBRS, M.HsaIIIA, DNMT3A2) Copy Product Info
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Synonyms: TBRS, M.HsaIIIA, DNMT3A2

Catalog No. TMAT-1653 Copy Product Info
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Anti-DNMT3A Monoclonal Antibody (4U476) is a Mouse antibody targeting DNMT3A. Anti-DNMT3A Monoclonal Antibody (4U476) can be used in IHC,FCM.

Anti-DNMT3A Monoclonal Antibody
(4U476)

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Product Introduction

Bioactivity
Description
Anti-DNMT3A Monoclonal Antibody (4U476) is a Mouse antibody targeting DNMT3A. Anti-DNMT3A Monoclonal Antibody (4U476) can be used in IHC,FCM.
SynonymsTBRS, M.HsaIIIA, DNMT3A2
Ig Type
IgG2a
Clone
4U476
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli.
Antigen Species
Human
Gene Name
DNMT3A
Gene ID
Protein Name
DNA (cytosine-5)-methyltransferase 3A
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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