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Synonyms: TBRS, M.HsaIIIA, DNMT3A2
Anti-DNMT3A Monoclonal Antibody
(4U476)

| Description | Anti-DNMT3A Monoclonal Antibody (4U476) is a Mouse antibody targeting DNMT3A. Anti-DNMT3A Monoclonal Antibody (4U476) can be used in IHC,FCM. |
| Synonyms | TBRS, M.HsaIIIA, DNMT3A2 |
| Ig Type | IgG2a |
| Clone | 4U476 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | DNMT3A |
| Gene ID | |
| Protein Name | DNA (cytosine-5)-methyltransferase 3A |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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