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Anti-SETD2 Monoclonal Antibody (5L227)
(Synonyms: SET2, p231HBP, LLS, KMT3A, HYPB, HSPC069, HIP-1, HIF-1, HBP231) Copy Product Info
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Synonyms: SET2, p231HBP, LLS, KMT3A, HYPB, HSPC069, HIP-1, HIF-1, HBP231
Catalog No. TMAT-1525 Copy Product Info
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Anti-SETD2 Monoclonal Antibody (5L227) is a Mouse antibody targeting SETD2. Anti-SETD2 Monoclonal Antibody (5L227) can be used in FCM.
Anti-SETD2 Monoclonal Antibody
(5L227)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-SETD2 Monoclonal Antibody (5L227) is a Mouse antibody targeting SETD2. Anti-SETD2 Monoclonal Antibody (5L227) can be used in FCM. |
| Synonyms | SET2, p231HBP, LLS, KMT3A, HYPB, HSPC069, HIP-1, HIF-1, HBP231 |
| Ig Type | IgG1 |
| Clone | 5L227 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008] |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human SETD2 (AA: 2054-2245) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | SETD2 |
| Gene ID | |
| Protein Name | Histone-lysine N-methyltransferase SETD2 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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