mac — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8507	MAC-545496		Antibacterial
	MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.		Antibacterial
T27971	MAC-0547630	MAC 0547630
	MAC-0547630 potent and selective inhibitor of UppS.
T71895	MAC-5576
	MAC-5576 a SARS-CoV-2 Protease inhibitor (IC50 = 81 nM).
T18721	MAC-VC-PABC-ST7612AA1		Others
	MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].		Others
TN1966	N-(3-Methoxybenzyl)Oleamide	N-Benzyloleamide,MAC 18:1	Antioxidant
	N-(3-Methoxybenzyl)Oleamide (MAC 18:1), an agmatine isolated from Lepidium meyenii, has pharmacological effects on exercise-induced fatigue, which may be related to the modulation of energy metabolism and improvement of ...		Antioxidant
T18231	MAC glucuronide linker-2		Others
	MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].		Others
T18230	MAC glucuronide linker-1		Others
	MAC glucuronide linker-1 is a nonclaevable ADC linker for antibody-drug-conjugations (ADCs).		Others
T11933	MAC13772		Others
	MAC13772 is a potent inhibitor of the enzyme BioA with an IC50 of 250 nM thereby inhibiting biotin biosynthesis. MAC13772 exhibits antibacterial activity.		Others
T18538	MAC glucuronide phenol-linked SN-38		Others
	MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].		Others
T18722	MAC glucuronide α-hydroxy lactone-linked SN-38		Others
	MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a cytotoxic drug linker that maintains a stabilized lactone form, showing efficacy against L540cy and Ramos cells, with IC50 values of 99 and ...		Others
T27972	MAC173979	MAC-173979,MAC 173979
	MAC173979 inhibits E. coli de novo PABA biosynthesis and growth.
T15947	MAC13243 HCl		Antibacterial
	MAC13243 HCl, an inhibitor of LolA, a periplasmic chaperone that transports lipoproteins from the inner membrane to the outer membrane, is an antimicrobial agent with specificity and significant inhibitory effects on Gra...		Antibacterial
T9915	Eculizumab		Complement System
	Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5		Complement System
T3638	Leukadherin-1		Integrin , Complement System
	Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.		Integrin , Complement System
T69305	Milataxel
	Milataxel is an orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of mi...
T69812	AFN941
	AFN941 is a staurosporine analog, acting as a Jak3-specific inhibitor.
T3583	Macozinone	PBTZ169	Antibacterial , DprE1
	Macozinone (PBTZ169) inhibits decaprenylphosphoryl-β-d-ribose 2′-oxidase (DprE1), more efficiently than BTZ043.		Antibacterial , DprE1
T3367	Macranthoidin B	Macranthoiside I	Others
	Macranthoidin B (Macranthoiside I), a saponin extracted from Flos Lonicerae is a main bioactive saponin in rat plasma (p.o.).		Others
T76776	Emactuzumab	RO 5509554,RG 7155	c-Fms , TAM Receptor
	Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has antitumor activity and inhibits activation of colony-stimulating fa...		c-Fms , TAM Receptor
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase