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Synonyms: TIE, JTK14
Anti-TIE1 Monoclonal Antibody
(9H277)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $298 | 7-10 days | 7-10 days | |
| 100 µL | $428 | 7-10 days | 7-10 days |
| Description | Anti-TIE1 Monoclonal Antibody (9H277) is a Mouse antibody targeting TIE1. Anti-TIE1 Monoclonal Antibody (9H277) can be used in WB,IHC. |
| Synonyms | TIE, JTK14 |
| Ig Type | IgG1 |
| Clone | 9H277 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of TIE1 on HepG2 cell lysate using anti-TIE1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CD68 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD68 antibody. Counter stained with hematoxylin. , ,![]() |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | TIE1 |
| Gene ID | |
| Protein Name | Tyrosine-protein kinase receptor Tie-1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 125 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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