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Anti-TIE1 Antibody (6A314)
😃Good
Catalog No. TMAC-04040
Alias tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE, JTK14
Anti-TIE1 Antibody (6A314) is a Mouse antibody targeting TIE1. Anti-TIE1 Antibody (6A314) can be used in WB,IHC.
Anti-TIE1 Antibody (6A314)
Anti-TIE1 Antibody (6A314)
😃Good
Catalog No. TMAC-04040Alias tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE, JTK14
Anti-TIE1 Antibody (6A314) is a Mouse antibody targeting TIE1. Anti-TIE1 Antibody (6A314) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $428 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-TIE1 Antibody (6A314) is a Mouse antibody targeting TIE1. Anti-TIE1 Antibody (6A314) can be used in WB,IHC. |
| Synonyms | tyrosine kinase with immunoglobulin-like and EGF-like domains 1, TIE, JTK14 |
| Clone | 6A314 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of TIE1 on human TIE1 recombinant protein using anti-TIE1 antibody at 1/1,000 dilution. 2. Western blot analysis of TIE1 on HEK293 (1) and RAN-hIgGFc transfected HEK293 (2) cell lysate using anti-TIE1 antibody at 1/1,000 dilution. 3. Western blot analysis of TIE1 on HepG2 cell lysate using anti-TIE1 antibody at 1/1,000 dilution. 4. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-CD68 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD68 antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:200-1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Receptor tyrosine kinases play key roles in signal transduction across cell surfaces in biological systems, including the vascular system. These receptors comprise a large and diverse family of catalytically related proteins that, on the basis of sequence and structural similarities, can be divided into several different evolutionary subfamilies. The cloning and characterization of Tie-1 (also designated Tie), a novel human endothelial cell surface receptor tyrosine kinase, has been reported. The extracellular domain of the predicted Tie-1 protein product has an unusual multidomain structure consisting of a cluster of three epidermal growth factor homology motifs localized between two immunoglobulin-like loops, which are followed by three fibronectin type III repeats next to the transmembrane region. An additional member of this family has been identified as Tie-2 (also designated Tek). Tie-1 and Tie-2 have been shown to be encoded by distinct genes and to represent members of a new class of receptor tyrosine kinases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 125 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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