Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-GM-CSF/CSF2 Antibody (4W819) (Synonyms: GM-CSF, GMCSF, CSF2, colony stimulating factor 2 (granulocyte-ma...)
Catalog No. TMAY-00083 Copy Product Info
🥰Excellent
Anti-GM-CSF/CSF2 Antibody (4W819) is a Mouse antibody targeting GM-CSF/CSF2. Anti-GM-CSF/CSF2 Antibody (4W819) can be used in ELISA(Cap).
Anti-GM-CSF/CSF2 Antibody (4W819)
Copy Product Info🥰Excellent
Catalog No. TMAY-00083
Synonyms GM-CSF, GMCSF, CSF2, colony stimulating factor 2 (granulocyte-macrophage)
Anti-GM-CSF/CSF2 Antibody (4W819) is a Mouse antibody targeting GM-CSF/CSF2. Anti-GM-CSF/CSF2 Antibody (4W819) can be used in ELISA(Cap).
Anti-GM-CSF/CSF2 Antibody
(4W819)
(4W819)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $70 | 7-10 days | 7-10 days | |
| 100 μL | $199 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GM-CSF/CSF2 Antibody (4W819) is a Mouse antibody targeting GM-CSF/CSF2. Anti-GM-CSF/CSF2 Antibody (4W819) can be used in ELISA(Cap). |
| Synonyms | GM-CSF, GMCSF, CSF2, colony stimulating factor 2 (granulocyte-macrophage) |
| Ig Type | Mouse IgG1 |
| Clone | 4W819 |
| Reactivity | Human |
| Specificity | Human GM-CSF/CSF2 |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GM-CSF / CSF2 (rh GM-CSF / CSF2; TMPY-02466; NP_000749.2; Ala18-Glu144). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. Several cell lineages in the reproductive tract and gestational tissues synthesise GM-CSF under direction by ovarian steroid hormones and signalling agents originating in male seminal fluid and the conceptus. The pre-implantation embryo, invading placental trophoblast cells and the abundant populations of leukocytes controlling maternal immune tolerance are all subject to GM-CSF regulation. GM-CSF stimulates the differentiation of hematopoietic progenitors to monocytes and neutrophils, and reduces the risk for febrile neutropenia in cancer patients. GM-CSF also has been shown to induce the differentiation of myeloid dendritic cells (DCs) that promote the development of T-helper type 1 (cellular) immune responses in cognate T cells. The active form of the protein is found extracellularly as a homodimer, and the encoding gene is localized to a related gene cluster at chromosome region 5q31 which is known to be associated with 5q-syndrome and acute myelogenous leukemia. As a part of the immune/inflammatory cascade, GM-CSF promotes Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity, and thus worthy of consideration for therapeutic target. GM-CSF has been utilized in the clinical management of multiple disease processes. Most recently, GM-CSF has been incorporated into the treatment of malignancies as a sole therapy, as well as a vaccine adjuvant. While the benefits of GM-CSF in this arena have been promising, recent reports have suggested the potential for GM-CSF to induce immune suppression and, thus, negatively impact outcomes in the management of cancer patients. GM-CSF deficiency in pregnancy adversely impacts fetal and placental development, as well as progeny viability and growth after birth, highlighting this cytokine as a central maternal determinant of pregnancy outcome with clinical relevance in human fertility.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human GM-CSF / CSF2 Protein (TMPY-02466) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-GM-CSF/CSF2 Antibody (4W819) | purchase Anti-GM-CSF/CSF2 Antibody (4W819) | Anti-GM-CSF/CSF2 Antibody (4W819) cost | order Anti-GM-CSF/CSF2 Antibody (4W819)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.