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Anti-AKT1 Antibody (7N506)
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Catalog No. TMAC-00122
Anti-AKT1 Antibody (7N506) is a Mouse antibody targeting AKT1. Anti-AKT1 Antibody (7N506) can be used in WB,ICC,IHC,FCM.
Anti-AKT1 Antibody (7N506)
Anti-AKT1 Antibody (7N506)
😃Good
Catalog No. TMAC-00122
Anti-AKT1 Antibody (7N506) is a Mouse antibody targeting AKT1. Anti-AKT1 Antibody (7N506) can be used in WB,ICC,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $428 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-AKT1 Antibody (7N506) is a Mouse antibody targeting AKT1. Anti-AKT1 Antibody (7N506) can be used in WB,ICC,IHC,FCM. |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:2000; IHC: 1:100-200; ICC: 1:100-200; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mice lacking Akt1 display a 25% reduction in body mass, indicating that Akt1 is critical for transmitting growth-promoting signals, most likely via the igf1 receptor. Mice lacking Akt1 are also resistant to cancer: They experience considerable delay in tumor growth initiated by the large T antigen or the Neuoncogene. |
| Conjucates | Unconjugated |
| Immunogen | Peptide |
| Antigen Species | Peptide |
| Uniprot ID |
| Molecular Weight | Theoretical: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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