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Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57)

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Catalog No. TMAC-02246

Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) is a Mouse antibody targeting Isocitrate dehydrogenase/IDH1. Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) can be used in WB,IHC.

Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57)

Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57)

😃Good
Catalog No. TMAC-02246
Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) is a Mouse antibody targeting Isocitrate dehydrogenase/IDH1. Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4277-10 days
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Product Introduction

Bioactivity
Description
Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) is a Mouse antibody targeting Isocitrate dehydrogenase/IDH1. Anti-Isocitrate dehydrogenase/IDH1 Antibody (9Q57) can be used in WB,IHC.
Reactivity
Human,zebrafish
Application
Recommended Dose
WB: 1:1000; IHC: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIsocitrate dehydrogenase (IDH) is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate (α-ketoglutarate) and CO2. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD+ to NADH in the mitochondria. The isoforms IDH1 and IDH2 catalyze the same reaction outside the context of the citric acid cycle and use NADP+ as a cofactor instead of NAD+. They localize to the cytosol as well as the mitochondrion and peroxisome. Mutations in IDH1 are also implicated in cancer. Originally mutations in IDH1 were detected in an integrated genomic analysis of human glioblastoma multiforme. In addition to being mutated in diffuse gliomas, IDH1 has also been shown to harbor mutations in human acute myeloid leukemia (AML).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 47 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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