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Anti-CD131 Antibody (8L902) is a Rabbit antibody targeting CD131. Anti-CD131 Antibody (8L902) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-CD131 Antibody (8L902) is a Rabbit antibody targeting CD131. Anti-CD131 Antibody (8L902) can be used in ELISA. |
Alias | colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8L902 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD131 / CSF2RB / IL3RB / IL5RB (rh CD131 / CSF2RB / IL3RB / IL5RB ; TMPY-01650; NP_000386.1; Met 1-Trp 443). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Colony stimulating factor 2 receptor, beta, low-affinity (CSF2RB) also known as CD131 antigen (CD131), cytokine receptor common subunit beta, GM-CSF/IL-3/IL-5 receptor common beta-chain, interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (IL3RB), is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this protein have been reported to be associated with protein alveolar proteinosis (PAP). CD131 belongs to the type I cytokine receptor family. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Defects in CD131/CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5). SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CD131 / CSF2RB / IL3RB / IL5RB protein (TMPY-01650) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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