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Anti-CD59 Monoclonal Antibody (9D183)
(Synonyms: p18-20, MSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIF, HRF-20, HRF20, G344, EL32, EJ30, EJ16, 1F5, 16.3A5) Copy Product Info
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Synonyms: p18-20, MSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIF, HRF-20, HRF20, G344, EL32, EJ30, EJ16, 1F5, 16.3A5
Catalog No. TMAT-0434 Copy Product Info
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Anti-CD59 Monoclonal Antibody (9D183) is a Mouse antibody targeting CD59. Anti-CD59 Monoclonal Antibody (9D183) can be used in IHC,IF,FCM.
Anti-CD59 Monoclonal Antibody
(9D183)
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| Description | Anti-CD59 Monoclonal Antibody (9D183) is a Mouse antibody targeting CD59. Anti-CD59 Monoclonal Antibody (9D183) can be used in IHC,IF,FCM. |
| Synonyms | p18-20, MSK21, MIRL, MIN3, MIN2, MIN1, MIC11, MEM43, MAC-IP, MACIF, HRF-20, HRF20, G344, EL32, EJ30, EJ16, 1F5, 16.3A5 |
| Ig Type | IgG1 |
| Clone | 9D183 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000; IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CD59 |
| Gene ID | |
| Protein Name | CD59 glycoprotein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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