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Anti-HLA-E Antibody (6I53)

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Catalog No. TMAC-01974

Anti-HLA-E Antibody (6I53) is a Mouse antibody targeting HLA-E. Anti-HLA-E Antibody (6I53) can be used in WB,IP,FCM.

Anti-HLA-E Antibody (6I53)

Anti-HLA-E Antibody (6I53)

😃Good
Catalog No. TMAC-01974
Anti-HLA-E Antibody (6I53) is a Mouse antibody targeting HLA-E. Anti-HLA-E Antibody (6I53) can be used in WB,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4267-10 days
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Product Introduction

Bioactivity
Description
Anti-HLA-E Antibody (6I53) is a Mouse antibody targeting HLA-E. Anti-HLA-E Antibody (6I53) can be used in WB,IP,FCM.
Reactivity
Human
Application
Recommended Dose
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) FCMM: 1 μg per 1 x 106 cells; FCM: 1 μg per 1 x 106 cells
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMajor histocompatibility complex (MHC) molecules, which include human leukocyte antigens (HLAs), form an integral part of the immune response system. They are cell surface receptors that bind foreign peptides and present them to cytotoxic T lymphocytes (CTLs). MHC class I molecules consist of two polypeptide chains, an α or heavy chain and a non-covalently associated pro- tein, β-2-Microglobulin. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-A is a MHC class I heavy chain molecule that plays a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. HLA-B and HLA-C are proteins encod- ed by closely related genes that also exist in the MHC class I. HLA-E belongs to the HLA class I heavy chain paralog. HLA-E is a heterodimer consisting of a heavy chain and a light chain; the heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant HLA-E of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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