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Anti-CASP8 Monoclonal Antibody (8Z123)
(Synonyms: MGC78473, MCH5, MACH, FLJ17672, FLICE, Casp-8, CAP4, ALPS2B) Copy Product Info
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Synonyms: MGC78473, MCH5, MACH, FLJ17672, FLICE, Casp-8, CAP4, ALPS2B
Catalog No. TMAT-0211 Copy Product Info
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Anti-CASP8 Monoclonal Antibody (8Z123) is a Mouse antibody targeting CASP8. Anti-CASP8 Monoclonal Antibody (8Z123) can be used in WB,IHC,FCM.
Anti-CASP8 Monoclonal Antibody
(8Z123)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CASP8 Monoclonal Antibody (8Z123) is a Mouse antibody targeting CASP8. Anti-CASP8 Monoclonal Antibody (8Z123) can be used in WB,IHC,FCM. |
| Synonyms | MGC78473, MCH5, MACH, FLJ17672, FLICE, Casp-8, CAP4, ALPS2B |
| Ig Type | IgG1 |
| Clone | 8Z123 |
| Reactivity | Human,Mouse,Monkey,Rat |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human CASP8 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CASP8 |
| Gene ID | |
| Protein Name | Caspase-8 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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