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Anti-TGFBR3 Antibody (5X141) is a Mouse antibody targeting TGFBR3. Anti-TGFBR3 Antibody (5X141) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $426 | 7-10 days |
Description | Anti-TGFBR3 Antibody (5X141) is a Mouse antibody targeting TGFBR3. Anti-TGFBR3 Antibody (5X141) can be used in WB. |
Synonyms | βglycan, transforming growth factor, β receptor III, transforming growth factor, beta receptor III, BGCAN, betaglycan |
Clone | 5X141 |
Reactivity | Human,Mouse |
Application | |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
Research Background | A total of three members of the TGFβ family, TGFβ1, TGFβ2 and TGFβ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFβs mediate their activity by high affinity binding to the type II receptor transmembrane protein with a cytoplasmic serine-threonine kinase domain. TGFβ RIII (transforming growth factor beta receptor type 3), also known as TGFBR3 or TGFR-3, is an 850 amino acid secreted and single-pass type I membrane protein that contains one ZP domain and may assist in capturing TGFβ for presentation to signaling receptors. TGFβ RIII undergoes post-translational modification by glycosaminoglycan groups (GAG) and is encoded by a gene that maps to human chromosome 1p22.2. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 93 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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