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Anti-AXL Antibody (2U404) is a Mouse antibody targeting AXL. Anti-AXL Antibody (2U404) can be used in WB,ICC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $426 | 7-10 days |
Description | Anti-AXL Antibody (2U404) is a Mouse antibody targeting AXL. Anti-AXL Antibody (2U404) can be used in WB,ICC. |
Reactivity | Human |
Application | |
Recommended Dose | WB: 1:500; ICC: 1:200-500 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProG affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: human UFO 1-150 aa |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 98 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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