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Anti-ITGAM Monoclonal Antibody (7H720)

(Synonyms: SLEB6, MO1A, MAC1A, MAC-1, CR3A, CD11B) Copy Product Info
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Synonyms: SLEB6, MO1A, MAC1A, MAC-1, CR3A, CD11B

Catalog No. TMAT-0805 Copy Product Info
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Anti-ITGAM Monoclonal Antibody (7H720) is a Mouse antibody targeting ITGAM. Anti-ITGAM Monoclonal Antibody (7H720) can be used in IHC,IF,FCM.

Anti-ITGAM Monoclonal Antibody
(7H720)

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Product Introduction

Bioactivity
Description
Anti-ITGAM Monoclonal Antibody (7H720) is a Mouse antibody targeting ITGAM. Anti-ITGAM Monoclonal Antibody (7H720) can be used in IHC,IF,FCM.
SynonymsSLEB6, MO1A, MAC1A, MAC-1, CR3A, CD11B
Ig Type
IgG1
Clone
7H720
Reactivity
Human
Application
Recommended Dose
IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human ITGAM (AA: 623-728) expressed in E. Coli.
Antigen Species
Human
Gene Name
ITGAM
Gene ID
Protein Name
Integrin alpha-M
Uniprot ID
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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