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Anti-Contactin 3 Antibody (8J989)
😃Good
Catalog No. TMAY-00403
Alias contactin 3 (plasmacytoma associated)
Anti-Contactin 3 Antibody (8J989) is a Mouse antibody targeting Contactin 3. Anti-Contactin 3 Antibody (8J989) can be used in ELISA.
Anti-Contactin 3 Antibody (8J989)
Anti-Contactin 3 Antibody (8J989)
😃Good
Catalog No. TMAY-00403Alias contactin 3 (plasmacytoma associated)
Anti-Contactin 3 Antibody (8J989) is a Mouse antibody targeting Contactin 3. Anti-Contactin 3 Antibody (8J989) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Contactin 3 Antibody (8J989) is a Mouse antibody targeting Contactin 3. Anti-Contactin 3 Antibody (8J989) can be used in ELISA. |
| Alias | contactin 3 (plasmacytoma associated) |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8J989 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Contactin-3 (rh CNTN3; TMPY-00723; Met1-Ser1002,708Asp/Asn; NP_065923.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography . |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2 (TAG-1), Contactin-3 (BIG-1), BIG-2, Contactin-5 (NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-3, also known as CNTN3 (BIG-1 in rat and PANG in mouse), is a GPI-linked glycoprotein that is expressed on cerebellar Purkinje cells, amygdaloid and thalamic neurons and olfactory granule cells. In the brain, Contactin-3 is expressed in frontal lobe, occipital lobe, cerebellum and amygdala. Contactin-3 contains 4 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. Human Contactin-3 shares 92% aa identity with mouse Contactin-3. The exact function of Contactin-3 is unclear. Contactin-3 may mediate cell-cell interaction and may promote neurite outgrowth. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CNTN3 protein (TMPY-00723) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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