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Anti-DIS3L2 Antibody (3M441)
😃Good
Catalog No. TMAC-01149
Alias MGC42174, FLJ36974, DIS3-like exonuclease 2, Dis3l2, DIS3 mitotic control homolog like 2, DIS3 mitotic control homolog (S. cerevisiae) like 2, DIS3 L2, DI3L2_HUMAN
Anti-DIS3L2 Antibody (3M441) is a Mouse antibody targeting DIS3L2. Anti-DIS3L2 Antibody (3M441) can be used in WB,IHC,FCM.
Anti-DIS3L2 Antibody (3M441)
Anti-DIS3L2 Antibody (3M441)
😃Good
Catalog No. TMAC-01149Alias MGC42174, FLJ36974, DIS3-like exonuclease 2, Dis3l2, DIS3 mitotic control homolog like 2, DIS3 mitotic control homolog (S. cerevisiae) like 2, DIS3 L2, DI3L2_HUMAN
Anti-DIS3L2 Antibody (3M441) is a Mouse antibody targeting DIS3L2. Anti-DIS3L2 Antibody (3M441) can be used in WB,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-DIS3L2 Antibody (3M441) is a Mouse antibody targeting DIS3L2. Anti-DIS3L2 Antibody (3M441) can be used in WB,IHC,FCM. |
| Synonyms | MGC42174, FLJ36974, DIS3-like exonuclease 2, Dis3l2, DIS3 mitotic control homolog like 2, DIS3 mitotic control homolog (S. cerevisiae) like 2, DIS3 L2, DI3L2_HUMAN |
| Clone | 3M441 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of DIS3L2 on human DIS3L2 recombinant protein using anti-DIS3L2 antibody at 1/1,000 dilution. 2. Western blot analysis of DIS3L2 on HEK293 (1) and DIS3L2-hIgGFc transfected HEK293 (2) cell lysate using anti-DIS3L2 antibody at 1/1,000 dilution. 3. Western blot analysis of DIS3L2 on Hela (1) and HepG2 (2) cell lysate using anti-DIS3L2 antibody at 1/1,000 dilution. 4. Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue using anti-DIS3L2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-DIS3L2 antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of Jurkat cells with DIS3L2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3' to 5' exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3' region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3' processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 100 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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