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Anti-KRT16 Antibody (5M214)

😃Good
Catalog No. TMAC-00867
Alias type I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16)

Anti-KRT16 Antibody (5M214) is a Mouse antibody targeting KRT16. Anti-KRT16 Antibody (5M214) can be used in IHC.

Anti-KRT16 Antibody (5M214)

Anti-KRT16 Antibody (5M214)

😃Good
Catalog No. TMAC-00867Alias type I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16)
Anti-KRT16 Antibody (5M214) is a Mouse antibody targeting KRT16. Anti-KRT16 Antibody (5M214) can be used in IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-KRT16 Antibody (5M214) is a Mouse antibody targeting KRT16. Anti-KRT16 Antibody (5M214) can be used in IHC.
Synonymstype I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16)
Clone
5M214
Reactivity
Human,Mouse,Rat
Verified Activity
1. IHC staining of human gullet cancer tissue with CK16 mouse mAb diluted at 1:200.
Application
Recommended Dose
IHC: 1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationAffinity purification using immunogen.
AppearanceLiquid
FormulationMouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundKeratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
Chemical Properties
Molecular WeightActual: 51 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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