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Anti-KRT16 Antibody (5M214) is a Mouse antibody targeting KRT16. Anti-KRT16 Antibody (5M214) can be used in IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-KRT16 Antibody (5M214) is a Mouse antibody targeting KRT16. Anti-KRT16 Antibody (5M214) can be used in IHC. |
Synonyms | type I cytoskeletal 16, KRT16A, KRT16, Keratin-16 (K16), Keratin, type I cytoskeletal 16, Cytokeratin-16 (CK-16) |
Clone | 5M214 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. IHC staining of human gullet cancer tissue with CK16 mouse mAb diluted at 1:200. |
Application | |
Recommended Dose | IHC: 1:200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | Affinity purification using immunogen. |
Appearance | Liquid |
Formulation | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating. |
Conjucates | Unconjugated |
Uniprot ID |
Molecular Weight | Actual: 51 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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