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MAC13243 HCl, an inhibitor of LolA, a periplasmic chaperone that transports lipoproteins from the inner membrane to the outer membrane, is an antimicrobial agent with specificity and significant inhibitory effects on Gram-negative bacteria.

MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.

MAC13772 is a potent inhibitor of the enzyme BioA with an IC50 of 250 nM, thereby inhibiting biotin biosynthesis and exhibiting antibacterial activity.

MAC glucuronide linker-1 is an ADC linker that can be used in the construction of antibody-coupled reactive molecules (ADCs) with the advantage of being cleavable.

MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].

MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].

MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a cytotoxic drug linker that maintains a stabilized lactone form, demonstrating efficacy against L540cy and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively[1].

MAC-5576 a SARS-CoV-2 Protease inhibitor (IC50 = 81 nM).

MacConkey Agar (MAC) is used for the selective isolation of enteric pathogens. The composition for 1 liter of MacConkey Agar includes: peptone (20.0 g), lactose (10.0 g), bile salts No. 3 (1.5 g), sodium chloride (5.0 g), neutral red (0.03 g), crystal violet (0.001 g), and agar (15.0 g).

Complement factor D-IN-1 is a potent and selective small-molecule reversible Factor D inhibitor, with IC50 values of 0.006 μM in the FD Thioesterolytic Fluorescent Assay and 0.05 μM in the MAC Deposition Assay.

Milataxel is an orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, milataxel appears to be a poor substrate for the multidrug resistance (MDR) membrane-associated P-glycoprotein (P-gp) efflux pump and may be useful for treating multidrug-resistant tumors. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).This compound is unstable in powder form and other related salt forms are recommended.

Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte motility and transendothelial migration; reduces inflammation.

AFN941 is a staurosporine analog, acting as a Jak3-specific inhibitor.

N-(3-Methoxybenzyl)Oleamide (MAC 18:1), an agmatine isolated from Lepidium meyenii, has pharmacological effects on exercise-induced fatigue, which may be related to the modulation of energy metabolism and improvement of antioxidant status.

Mal-va-mac-SN38 is a conjugate molecule functioning as an ADC (Antibody-Drug Conjugate) drug-linker. This compound comprises the cytotoxic ADC agent SN-38 and a linker. Once inside the body, Mal-va-mac-SN38 rapidly forms a covalent bond with endogenous albumin, resulting in the formation of HSA-va-mac-SN38. It demonstrates remarkable stability in human plasma and exhibits both antitumor and antimetastatic properties.

Anti-Mouse/Human Mac-2/Galectin-3 Antibody (TIB-166) is an IgG2a, κ inhibitor derived from rats, targeting mouse or human Mac-2/Galectin-3.

Macropin (MAC-1 peptide) is an antimicrobial peptide found in the venom of the solitary bee Macropis fulvipes. It exhibits antibacterial properties against both Gram-positive and Gram-negative bacteria, demonstrates inhibitory effects on fungi, and possesses moderate hemolytic activity on human red blood cells. Macropin is utilized in research for anti-infective therapies.

MAC-VC-PABC-ST7612AA1 is a part of antibody drug conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity[1].

mAC2-IN-1 (compound 14) is a potent and selective inhibitor of human adenylyl cyclase (mAC) with an IC50 value of 4.45 μM. It exhibits significantly lower activity against mAC1 and mAC5.

MAC-0547630 potent and selective inhibitor of UppS.

MAC173979 inhibits E. coli de novo PABA biosynthesis and growth.

Abemaciclib metabolite M20 (CDK4/6-IN-4) is an active metabolite of Abemaciclib. Abemaciclib metabolite M20 is a selective CDK4/6 inhibitor and can be used for researches on the treatment of cancer.

Macropa-NCS is a macropa bifunctional analog with antitumor activity and can be used to study prostate cancer.

Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.