T13572 |
Cancer-Targeting Compound 1
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Others
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Cancer-Targeting Compound 1 can be used in the study of hormone-related cancers, including the treatment or prevention o... |
T2455 |
PFK-015
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PFK15,PFK 015 |
Autophagy
,
Glucokinase
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PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM). |
T22336 |
Galloflavin
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Dehydrogenase
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Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. G... |
T9963 |
MPT0B390
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HDAC
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MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis. |
T41255 |
Specific PXR antagonist 70
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Others
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Specific PXR antagonist 70 is a selective pregnane X receptor (PXR) antagonist with an IC50 of 540 nM and Ki of 390 nM f... |
TN1046 |
Murrayone
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Others
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Murrayone, a coumarin-containing compound extracted from M. paniculata, is the most bioactive substance in this species ... |
T3755 |
Pinostilbene
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Others
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Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA. |
T8432 |
ASP4132
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AMPK
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ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity. |
T60028 |
MM41
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DNA/RNA Synthesis
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MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 panc... |
T9552 |
BAZ1A-IN-1
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Epigenetic Reader Domain
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BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good ant... |
T22263 |
Bavdegalutamide
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ARV-110 |
Androgen Receptor
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ARV-110 is an oral degrader of androgen receptor PROTAC for prostate cancer treatment. |
T9929 |
Ramucirumab
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VEGFR
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Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. |
T6816 |
DASA-58
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PKM
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DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator. |
TN7020 |
Astragenol
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Others
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Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inf... |
T8973 |
HS-1793
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Others
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HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growt... |
T16522 |
Phenoxodiol
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Idronoxil,Haginin E,Dehydroequol |
Caspase
,
IAP
,
p53
,
Apoptosis
,
Topoisomerase
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Phenoxodiol is a synthetic analog of Genestein and activates the mitochondrial caspase system. Phenoxodiol causes cell c... |
T2325 |
Neratinib
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HKI-272 |
EGFR
,
HER
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Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), r... |
T5S0777 |
Phellodendrine chloride
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Others
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Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migra... |
T1394 |
Ibuprofen
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(±)-Ibuprofe,Advil,Motrin,Brufen |
COX
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Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic... |
T17258 |
WRG-28
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Discoidin Domain Receptor (DDR)
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WRG-28 is a potent and selective, allosteric discoidin domain receptor 2 (ddr2) inhibitor(IC50 : 230 nM) |