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Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12)
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Catalog No. T9901A-1992
Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) is a rat-derived inhibitory antibody that targets mouse PD-1 and blocks its binding to both PD-L1 and PD-L2 ligands.It is suitable for cancer and immunology research, including CT26 tumors and pancreatic cancer models .
Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12)
Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12)
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Purity: 95%
Catalog No. T9901A-1992
Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) is a rat-derived inhibitory antibody that targets mouse PD-1 and blocks its binding to both PD-L1 and PD-L2 ligands.It is suitable for cancer and immunology research, including CT26 tumors and pancreatic cancer models .
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $685 | 4-6 weeks | 4-6 weeks | |
| 5 mg | $1,500 | 4-6 weeks | 4-6 weeks | |
| 10 mg | Preferential | 4-6 weeks | 4-6 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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| Description | Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) is a rat-derived inhibitory antibody that targets mouse PD-1 and blocks its binding to both PD-L1 and PD-L2 ligands.It is suitable for cancer and immunology research, including CT26 tumors and pancreatic cancer models . |
| In vitro | Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) (10 μg/mL, 7 days), when combined with anti-CTLA-4,increases the production of IFN-γ cytokine and the expression of Ki-67 in CD8+CTLA-4+PD-1+ tumor-infiltrating lymphocytes from CT26 tumors [1]. |
| In vivo | Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) (200 μg, intraperitoneal injection on days 10, 13 and 16) combined with anti-CTLA-4 induces tumor regression in CT26/ID8-VEGF tumor-bearing mice [1]. Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) (100 μg, intraperitoneal injection on days 1, 3 and 5 after BRAF inhibitor administration) combined with a BRAF inhibitor inhibits tumor growth and prolongs survival in BP tumor-bearing mice [2]. Anti-Mouse PD-1/CD279 (D265A) Antibody (29F.1A12) (200 μg, intraperitoneal injection on days 4, 7 and 10) combined with a PRIP1 inhibitor protects mice against primary pancreatic cancer and liver metastasis [3]. |
| Clone | 29F.1A12 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PD-1/CD279 |
| Molecular Weight | 150 kDa |
| Isotype | Mouse IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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