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Landogrozumab (Synonyms: LY2495655, LY 2495655, Anti-GDF8 / Myostatin Reference Antibody)

Catalog No. T9901A-060 Copy Product Info
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Landogrozumab (LY2495655) is a humanized anti-Growth Differentiation Factor-8 (GDF-8) monoclonal antibody that improves muscle size and may be used to study cancer and neurological disorders.

Landogrozumab

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Catalog No. T9901A-060
Synonyms LY2495655, LY 2495655, Anti-GDF8 / Myostatin Reference Antibody

Landogrozumab (LY2495655) is a humanized anti-Growth Differentiation Factor-8 (GDF-8) monoclonal antibody that improves muscle size and may be used to study cancer and neurological disorders.

Landogrozumab
Cas No. 1391726-30-9
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Purity:99% (SDS-PAGE); 97.5% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Landogrozumab (LY2495655) is a humanized anti-Growth Differentiation Factor-8 (GDF-8) monoclonal antibody that improves muscle size and may be used to study cancer and neurological disorders.
In vivo
Landogrozumab administered as a single intravenous injection at doses of 3 mg/kg and 15 mg/kg affected muscle mass in aged mice with Duchenne muscular dystrophy. [1]
SynonymsLY2495655, LY 2495655, Anti-GDF8 / Myostatin Reference Antibody
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetGDF8/Myostatin
Chemical Properties
Molecular Weight142.86 kDa
Cas No.1391726-30-9
Antibody Information
IsotypeHuman IgG4 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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