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L-Octanoylcarnitine hydrochloride

Catalog No. T77262 Copy Product Info
Purity: 99.91%
🥰Excellent
L-Octanoylcarnitine hydrochloride (C8:0) is a medium-chain acylcarnitine and a physiologically active plasma metabolite of octanoylcarnitine. It serves as an essential intermediate in the mitochondrial beta-oxidation pathway, facilitating the transport of medium-chain fatty acids across the mitochondrial membrane. It is widely utilized in research concerning breast cancer metabolism, arterial stiffness in overweight individuals, and mitochondrial dysfunction. Elevated levels of C8 carnitine are often indicative of incomplete fatty acid oxidation and are closely linked to oxidative stress and metabolic disorders.

L-Octanoylcarnitine hydrochloride

Copy Product Info
🥰Excellent
Catalog No. T77262

L-Octanoylcarnitine hydrochloride (C8:0) is a medium-chain acylcarnitine and a physiologically active plasma metabolite of octanoylcarnitine. It serves as an essential intermediate in the mitochondrial beta-oxidation pathway, facilitating the transport of medium-chain fatty acids across the mitochondrial membrane. It is widely utilized in research concerning breast cancer metabolism, arterial stiffness in overweight individuals, and mitochondrial dysfunction. Elevated levels of C8 carnitine are often indicative of incomplete fatty acid oxidation and are closely linked to oxidative stress and metabolic disorders.

L-Octanoylcarnitine hydrochloride
Cas No. 54377-02-5
Other Forms of L-Octanoylcarnitine hydrochloride:
Pack SizePriceUSA StockGlobal StockQuantity
5 mg$40-In Stock
10 mg$64-In Stock
25 mg$152-In Stock
50 mg$255-In Stock
100 mg$396-In Stock
1 mL x 10 mM (in DMSO)$44-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.91%
Appearance:Solid
Color:White
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
L-Octanoylcarnitine hydrochloride (C8:0) is a medium-chain acylcarnitine and a physiologically active plasma metabolite of octanoylcarnitine. It serves as an essential intermediate in the mitochondrial beta-oxidation pathway, facilitating the transport of medium-chain fatty acids across the mitochondrial membrane. It is widely utilized in research concerning breast cancer metabolism, arterial stiffness in overweight individuals, and mitochondrial dysfunction. Elevated levels of C8 carnitine are often indicative of incomplete fatty acid oxidation and are closely linked to oxidative stress and metabolic disorders.
In vitro
L-Octanoylcarnitine hydrochloride (0.2 mM) induces H2O2 release in mitochondria, suggesting it promotes oxidative stress by interfering with the electron transport chain, a mechanism relevant to neurodegeneration and metabolic damage [1].
In vivo
In obesity models, L-Octanoylcarnitine hydrochloride dysregulation is linked to impaired detrusor mitochondrial function and bladder dysfunction [2].
Chemical Properties
Molecular Weight323.86
FormulaC15H30ClNO4
Cas No.54377-02-5
Smiles[C@H](OC(CCCCCCC)=O)(C[N+](C)(C)C)CC(O)=O.[Cl-]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (247.02 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0878 mL15.4388 mL30.8775 mL154.3877 mL
5 mM0.6176 mL3.0878 mL6.1755 mL30.8775 mL
10 mM0.3088 mL1.5439 mL3.0878 mL15.4388 mL
20 mM0.1544 mL0.7719 mL1.5439 mL7.7194 mL
50 mM0.0618 mL0.3088 mL0.6176 mL3.0878 mL
100 mM0.0309 mL0.1544 mL0.3088 mL1.5439 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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