Shopping Cart

Your shopping cart is currently empty

CFT8634

Name: CFT8634
Brand: TargetMol
SKU: T73425
Price: 268 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T73425Cas No. 2704617-96-7

CFT8634 is an orally active and selective degrader targeting BRD9, with effects on the proliferation of SMARCB1-deficient cancer cell lines. CFT8634 induces the formation of a ternary complex with BRD9 and E3 ligase, inducing BRD9 ubiquitination and subsequent degradation by the proteasome.

CFT8634

Copy Product Info

😃Good

Purity: 99.95%

Catalog No. T73425Cas No. 2704617-96-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$268	-	In Stock
5 mg	$679	-	In Stock
10 mg	$1,070	-	In Stock
25 mg	$1,980	-	In Stock
50 mg	$3,430	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.95%

Appearance:Solid

Color:Brown

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	710.79
Formula	C₃₇H₄₅F₃N₆O₅
Cas No.	2704617-96-7
Smiles	CC=1C(C2=CC(OC)=C(CN3CC(F)(F)[C@H](CC3)N4CCN(CC4)C5=C(F)C=C(N[C@@H]6C(=O)NC(=O)CC6)C=C5)C(OC)=C2)=CN(C)C(=O)C1C

Storage & Solubility Information

Storage

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (140.69 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (4.64 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4069 mL	7.0344 mL	14.0689 mL	70.3443 mL
5 mM	0.2814 mL	1.4069 mL	2.8138 mL	14.0689 mL
10 mM	0.1407 mL	0.7034 mL	1.4069 mL	7.0344 mL
20 mM	0.0703 mL	0.3517 mL	0.7034 mL	3.5172 mL
50 mM	0.0281 mL	0.1407 mL	0.2814 mL	1.4069 mL
100 mM	0.0141 mL	0.0703 mL	0.1407 mL	0.7034 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc