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Garetosmab
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Catalog No. T77019Cas No. 2097125-54-5
Alias REGN 2477
Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer.
Garetosmab
Garetosmab
😃Good
Catalog No. T77019Alias REGN 2477Cas No. 2097125-54-5
Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | In Stock | In Stock | |
| 5 mg | $787 | In Stock | In Stock | |
| 10 mg | $1,230 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,730 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:> 95%
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| Description | Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer. |
| In vitro | Specifically binding to and blocking signaling of activin proteins containing the inhibin βα subunit (activins A, AB, and AC), garetosmab (REGN 2477) has high affinity and specificity for activins A, AB, and AC in vitro. It does not bind or functionally inhibit other TGF-β family ligands that share the same activin receptor pathways, including activin B, inhibin A, BMP-2, BMP6, BMP9, BMP10, GDF8, and GDF11[1]. |
| Synonyms | REGN 2477 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | INHBA/Activin A |
| Molecular Weight | 145.52 kDa |
| Cas No. | 2097125-54-5 |
| Color | Transparent |
| Appearance | Liquid |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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