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Garetosmab (Synonyms: REGN 2477)
Catalog No. T77019 Copy Product Info
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Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer.
Garetosmab
Copy Product Info🥰Excellent
Catalog No. T77019
Synonyms REGN 2477
Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer.
Garetosmab
Cas No. 2097125-54-5
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $328 | In Stock | In Stock | |
| 5 mg | $787 | In Stock | In Stock | |
| 10 mg | $1,230 | - | In Stock | |
| 25 mg | $1,980 | - | In Stock | |
| 50 mg | $2,730 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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| Description | Garetosmab (REGN 2477) is A whole-human IgG4 monoclonal antibody that selectively inhibits activin A and acts on COVID-19 44. Garetosmab has potential anti-cancer activity and can be used to study ossifying fibrous dysplasia (FOP) and cancer. |
| In vitro | Specifically binding to and blocking signaling of activin proteins containing the inhibin βα subunit (activins A, AB, and AC), garetosmab (REGN 2477) has high affinity and specificity for activins A, AB, and AC in vitro. It does not bind or functionally inhibit other TGF-β family ligands that share the same activin receptor pathways, including activin B, inhibin A, BMP-2, BMP6, BMP9, BMP10, GDF8, and GDF11[1]. |
| Synonyms | REGN 2477 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | INHBA/Activin A |
| Molecular Weight | 145.52 kDa |
| Cas No. | 2097125-54-5 |
| Isotype | Human IgG4SP kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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