BigGastrinI, human (TFA), is a gastrointestinal hormone comprised of 34 amino acids. It can serve as a potential substance in the study of conditions such as cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurological disorders, or cardiovascular diseases.

Big Gastrin I, human (TFA) (10 μg/mL, 6 days) reduces HBV replication by 11.3% in HepG2 cells carrying the hepatitis B virus (HBV) ayw strain genome, while preserving cell viability at 88.7%. In addition, at the same concentration for 24 hours, it can induce cell cycle arrest in the G0/G1 phase and trigger apoptosis in human A549 cells. Furthermore, treatment with 10 μg/mL for 22 hours inhibits 35% of cell migration in human endothelial cells (HUVEC).