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Necitumumab
(Synonyms: LY3012211, LY 3012211, IMC-11F8, IMC11F8) Copy Product Info
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Synonyms: LY3012211, LY 3012211, IMC-11F8, IMC11F8
Catalog No. T77459 Copy Product Info
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Necitumumab (IMC-11F8) is a human monoclonal antibody directed against the epidermal growth factor (EGF) receptor, an anti-angiogenic agent used in the treatment of advanced non-small cell lung cancer, and may be used in cancer research.
Cas No. 906805-06-9
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $179 | - | In Stock | |
| 5 mg | $546 | - | In Stock | |
| 10 mg | $868 | - | In Stock | |
| 25 mg | $1,280 | - | In Stock | |
| 50 mg | $1,730 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:97.9% (SDS-PAGE); 99.1% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Antibody Information
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| Description | Necitumumab (IMC-11F8) is a human monoclonal antibody directed against the epidermal growth factor (EGF) receptor, an anti-angiogenic agent used in the treatment of advanced non-small cell lung cancer, and may be used in cancer research. |
| Synonyms | LY3012211, LY 3012211, IMC-11F8, IMC11F8 |
| Reactivity | Human |
| Verified Activity | Immobilized Human EGFR Protein (His) (TMPY-00742) at 1 μg/mL (100 μL/well) can bind Necitumumab. The EC50 is 1.71 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | ERBB1/EGFR/HER1 |
| Molecular Weight | 144.81 kDa |
| Cas No. | 906805-06-9 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Necitumumab chemical structure | Necitumumab molecular weight
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