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U3-1784 (Synonyms: U31784)

Catalog No. T77453 Copy Product Info
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U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.

U3-1784

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Catalog No. T77453
Synonyms U31784

U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.

U3-1784
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$197-In Stock
5 mg$596-In Stock
10 mg$959-In Stock
25 mg$1,420-In Stock
50 mg$1,920-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:96.95% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.
Targets&IC50
FGFR4:2 nmol/L
In vitro
U3-1784 showed excellent specificity for FGFR4 and did not bind to other FGFR with Kd =0.3 nmol/L and IC50 value of 2 nmol/L. [1]
In vivo
U3-1784 (25 mg/kg) resulted in up to 90% tumor growth inhibition in a representative liver cancer mouse model of ten different xenografted tumors. [1]
SynonymsU31784
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetFGFR4/CD334
Chemical Properties
Molecular Weight143.22 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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