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U3-1784

😃Good
Catalog No. T77453
Alias U31784

U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.

U3-1784

U3-1784

😃Good
Catalog No. T77453Alias U31784
U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$197-In Stock
5 mg$596-In Stock
10 mg$959-In Stock
25 mg$1,420-In Stock
50 mg$1,920-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:96.95% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
U3-1784 is a humanized monoclonal antibody targeting CD334, with anti-cancer activity, used in liver cancer research.
Targets&IC50
FGFR4:2 nmol/L
In vitro
U3-1784 showed excellent specificity for FGFR4 and did not bind to other FGFR with Kd =0.3 nmol/L and IC50 value of 2 nmol/L. [1]
In vivo
U3-1784 (25 mg/kg) resulted in up to 90% tumor growth inhibition in a representative liver cancer mouse model of ten different xenografted tumors. [1]
SynonymsU31784
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetFGFR4/CD334
Chemical Properties
Molecular Weight143.22 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG1 lambda2
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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