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2′,2′-Difluorodeoxyuridine

🥰Excellent
Catalog No. T67291Cas No. 114248-23-6
Alias dFdU, 2',2'-Difluoro-2'-deoxyuridine

2′,2′-Difluorodeoxyuridine (dFdU), the major metabolite of Gemcitabine, exhibits anticancer and antitumor activities, shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.

2′,2′-Difluorodeoxyuridine

2′,2′-Difluorodeoxyuridine

🥰Excellent
Purity: 99.66%
Catalog No. T67291Alias dFdU, 2',2'-Difluoro-2'-deoxyuridineCas No. 114248-23-6
2′,2′-Difluorodeoxyuridine (dFdU), the major metabolite of Gemcitabine, exhibits anticancer and antitumor activities, shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30In StockIn Stock
10 mg$42In StockIn Stock
25 mg$74In StockIn Stock
50 mg$109In StockIn Stock
100 mg$163In StockIn Stock
200 mg$238-In Stock
1 mL x 10 mM (in DMSO)$41In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.66%
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Product Introduction

Bioactivity
Description
2′,2′-Difluorodeoxyuridine (dFdU), the major metabolite of Gemcitabine, exhibits anticancer and antitumor activities, shows radiosensitization under hypoxic conditions, and can be used to study pancreatic cancer.
SynonymsdFdU, 2',2'-Difluoro-2'-deoxyuridine
Chemical Properties
Molecular Weight264.18
FormulaC9H10F2N2O5
Cas No.114248-23-6
SmilesOC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C(F)(F)[C@@H]1O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (302.82 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.7853 mL18.9265 mL37.8530 mL189.2649 mL
5 mM0.7571 mL3.7853 mL7.5706 mL37.8530 mL
10 mM0.3785 mL1.8926 mL3.7853 mL18.9265 mL
20 mM0.1893 mL0.9463 mL1.8926 mL9.4632 mL
50 mM0.0757 mL0.3785 mL0.7571 mL3.7853 mL
100 mM0.0379 mL0.1893 mL0.3785 mL1.8926 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

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