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Wnt/β-catenin agonist 2

Name: Wnt/β-catenin agonist 2
Brand: TargetMol
SKU: T41094
Price: 49 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T41094Cas No. 943820-93-7

Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related to signal transduction and is closely related to cancer invasion and metastasis.

Wnt/β-catenin agonist 2

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Purity: 99.35%

Catalog No. T41094Cas No. 943820-93-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$49	In Stock	In Stock
5 mg	$118	In Stock	In Stock
10 mg	$196	In Stock	In Stock
25 mg	$334	In Stock	In Stock
50 mg	$472	In Stock	In Stock
100 mg	$672	In Stock	In Stock
500 mg	$1,330	-	In Stock
1 mL x 10 mM (in DMSO)	$113	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.35%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related to signal transduction and is closely related to cancer invasion and metastasis.
In vitro	Wnt/β-catenin agonist 2 acts as a stimulator of β-Catenin in the SW480 cell line, enhancing its activity. Moreover, it has been observed that Wnt/β-catenin agonist 2 exerts an influence on the differentiation of ST2 cells, promoting their transformation into osteoblasts [1].

Chemical Properties

Molecular Weight	272.26
Formula	C₁₃H₁₂N₄O₃
Cas No.	943820-93-7
Smiles	O=C(NCCn1cccn1)c1cc(on1)-c1ccco1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (550.94 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.35 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6730 mL	18.3648 mL	36.7296 mL	183.6480 mL
5 mM	0.7346 mL	3.6730 mL	7.3459 mL	36.7296 mL
10 mM	0.3673 mL	1.8365 mL	3.6730 mL	18.3648 mL
20 mM	0.1836 mL	0.9182 mL	1.8365 mL	9.1824 mL
50 mM	0.0735 mL	0.3673 mL	0.7346 mL	3.6730 mL
100 mM	0.0367 mL	0.1836 mL	0.3673 mL	1.8365 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc