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SMU-C68
🥰Excellent
Catalog No. T212119Cas No. 2677039-75-5
SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM). It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications.
SMU-C68
🥰Excellent
Catalog No. T212119Cas No. 2677039-75-5
SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM). It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications.
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Product Introduction
Bioactivity
Chemical Properties
| Description | SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 μM). It activates the NF-κB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-α and IL-1β. SMU-C68 holds potential for cancer research applications. |
| Molecular Weight | 411.54 |
| Formula | C21H21N3O2S2 |
| Cas No. | 2677039-75-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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