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Anti-FGFR1/CD331 Antibody
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Catalog No. T9901A-1357 Copy Product Info
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Anti-FGFR1/CD331 Antibody is a humanized monoclonal antibody targeting fibroblast growth factor receptor 1 (FGFR1/CD331). FGFR1 is a member of the receptor tyrosine kinase (RTK) family, playing a pivotal role in regulating cell proliferation, survival, migration, and angiogenesis. This antibody specifically binds to the extracellular domain of FGFR1, competitively blocking FGF ligand binding and subsequently inhibiting receptor autophosphorylation and the activation of downstream signaling pathways such as MAPK/ERK and PI3K/Akt. This mechanism effectively suppresses tumor growth and pathological hyperplasia driven by aberrant FGFR1 signaling, making it a valuable tool in research on solid tumors and the development of targeted cancer therapies.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-FGFR1/CD331 Antibody is a humanized monoclonal antibody targeting fibroblast growth factor receptor 1 (FGFR1/CD331). FGFR1 is a member of the receptor tyrosine kinase (RTK) family, playing a pivotal role in regulating cell proliferation, survival, migration, and angiogenesis. This antibody specifically binds to the extracellular domain of FGFR1, competitively blocking FGF ligand binding and subsequently inhibiting receptor autophosphorylation and the activation of downstream signaling pathways such as MAPK/ERK and PI3K/Akt. This mechanism effectively suppresses tumor growth and pathological hyperplasia driven by aberrant FGFR1 signaling, making it a valuable tool in research on solid tumors and the development of targeted cancer therapies. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | FGFR1/CD331 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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