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GSK3178022

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Catalog No. T9901A-1034

GSK3178022 is a human IgG1 monoclonal antibody (mAb) that targets LRP6. It inhibits the expression of the WNT target genes SP5 and AXIN2 and demonstrates antitumor activity in colorectal cancer RSPO fusion models. The recommended isotype control is HumanIgG1kappa, Isotype Control.

GSK3178022

GSK3178022

😃Good
Catalog No. T9901A-1034
GSK3178022 is a human IgG1 monoclonal antibody (mAb) that targets LRP6. It inhibits the expression of the WNT target genes SP5 and AXIN2 and demonstrates antitumor activity in colorectal cancer RSPO fusion models. The recommended isotype control is HumanIgG1kappa, Isotype Control.
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Instruction Manual of Inhibitory Antibody

Product Introduction

Bioactivity
Description
GSK3178022 is a human IgG1 monoclonal antibody (mAb) that targets LRP6. It inhibits the expression of the WNT target genes SP5 and AXIN2 and demonstrates antitumor activity in colorectal cancer RSPO fusion models. The recommended isotype control is HumanIgG1kappa, Isotype Control.
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Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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