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TargetMol | Compound Library

Mitochondrial Protection Compound Library

Catalog No. L5320

Mitochondria play a central role in maintaining cellular energy metabolism, regulating redox homeostasis, and participating in key biological processes such as apoptosis and calcium signaling. Mitochondrial dysfunction is closely associated with a wide range of diseases, including neurodegenerative disorders (such as Alzheimer’s disease and Parkinson’s disease), cardiovascular diseases, diabetes, cancer, and aging-related pathological processes. Therefore, targeting mitochondria to enhance their function or mitigate their damage has become an important strategy in drug discovery and development.
TargetMol’s Mitochondrial Protection Compound Library is a specially designed collection of compounds for the screening and study of mitochondrial protection activities. This library comprises 920 compounds with confirmed or potential mitochondrial protective effects. These structurally diverse small molecules act through mechanisms such as maintaining mitochondrial membrane potential (ΔΨm), reducing oxidative stress–induced damage, improving mitochondrial biogenesis, and promoting mitophagy. The collection includes, but is not limited to, mPTP inhibitors, PGC-1α agonists, DRP1 inhibitors, PINK1/Parkin pathway activators, Nrf2 activators, and polyphenols.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5320

Mitochondrial Protection Compound Library

sizeIn stock

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A collection of 920 compounds with potential or confirmed mitochondrial protective activity, suitable for high-throughput and high-content screening.
  • Detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are available for supply.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
NF-κB
Antibacterial
mTOR
Endogenous Metabolite
PPAR
ROS
PARP
PI3K
AMPK
Antioxidant
COX
Reactive Oxygen Species
Mitophagy
Nrf2
Akt
p38 MAPK
Cytochromes P450
Antifungal
HIV Protease
NO Synthase
TNF
Influenza Virus
Antibiotic
Tyrosinase
Caspase
ERK
Parasite
Interleukin
Virus Protease
JNK
Ferroptosis
DNA/RNA Synthesis
Wnt/beta-catenin
Glucosidase
Bcl-2 Family
Sirtuin
MMP
Anti-infection
STAT
Phosphatase
IL Receptor
PKC
glycosidase
SARS-CoV
Cholinesterase (ChE)
Estrogen Receptor/ERR
HSV
HDAC
DNA-PK
Calcium Channel
Lipoxygenase
GABA Receptor
Immunology/Inflammation related
TLR
CDK
TRP/TRPV Channel
Reductase
Dehydrogenase
Adrenergic Receptor
transporter
Beta Amyloid
5-HT Receptor
PDE
Xanthine Oxidase
Antifection
JAK
TGF-beta/Smad
IκB/IKK
AChR
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
HBV
Estrogen/progestogen Receptor
Drug Metabolite
GSK-3
Transferase
Monoamine Oxidase
ATPase
NOS
Topoisomerase
P-gp
Androgen Receptor
PKA
MAO
EGFR
Potassium Channel
SGLT
NOD-like Receptor (NLR)
Aryl Hydrocarbon Receptor
p53
UGT
ATM/ATR
Sodium Channel
VEGFR
Antiviral
S6 Kinase
Carbonic Anhydrase
Src
PERK
IGF-1R
Prostaglandin Receptor
Free radical scavengers
Fatty Acid Synthase
HMG-CoA Reductase
Microtubule Associated
Reverse Transcriptase
Angiotensin-converting Enzyme (ACE)
Ras
Pim
CaMK
FLT
Tyrosine Kinases
Glutathione Peroxidase
Amylase
PTEN
Cannabinoid Receptor
Dopamine Receptor
Proteasome
Integrin
RAAS
Phospholipase
HIF
NOD
Gamma-secretase
MAPK
Complement System
ADC Cytotoxin
Necroptosis
RANKL/RANK
Glucocorticoid Receptor
Bombesin Receptor
MEK
c-Kit
AhR
CD38
NR4A
IAP
PDGFR
Casein Kinase
p62
Hydroxylase
Chloride channel
Serine/threonin kinase
IRE1
LDL
FKBP
Retinoid Receptor
Histone Methyltransferase
RIP kinase
FAK
Histamine Receptor
Hedgehog/Smoothened
Epigenetic Reader Domain
Acyltransferase
GPCR
Adenosine Receptor
c-Myc
cAMP
Histone Acetyltransferase
Aromatase
MDM-2/p53
Platelet aggregation
ROS Kinase
PD-1/PD-L1
Glucokinase
Trk receptor
Syk
PGC-1α
PGK1
Advanced Glycation End Products
YAP
BACE
IFNAR
Cell wall
NADPH
OCT
Annexin A
Telomerase
Lipid
PSMA
PDK
stilbene oxidase
Histone Demethylase
ATG
iGluR
E1/E2/E3 Enzyme
ABC Transporter
Monoamine Transporter
FAAH
GluR
DNA
ATP Citrate Lyase
Proton pump
Monocarboxylate transporter
HCV Protease
MyD88
Arrestin
Cysteine Protease
FXR
FABP
Opioid Receptor
CXCR
Epoxide Hydrolase
Cadherin
Norepinephrine
STING
LRRK2
GluCls
Pyroptosis
Acetyl-CoA Carboxylase
CGRP Receptor
NADPH-oxidase
MLK
Adenylate cyclase
Bcr-Abl
P2X Receptor
Aurora Kinase
Thrombopoietin Receptor
PGE Synthase
Urea Transporter
NPC1L1
Serotonin Transporter
Beta-Secretase
HSP
Decarboxylase
FOXO
Adenosine Deaminase
Arginase
c-Met/HGFR
DYRK
CaSR
Liver X Receptor
PAK
MELK
GST
IRAK
Dynamin
Lipase
Serine Protease
Cell Cycle Arrest
MTH1
NMDAR
DPP-4
HCAR
Chk
OAT
RSV
c-Fms
Protease
PLK

Keywords