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TargetMol | Compound Library

Mitochondrial Protection Compound Library

Catalog No. L5320

Mitochondria play a central role in maintaining cellular energy metabolism, regulating redox homeostasis, and participating in key biological processes such as apoptosis and calcium signaling. Mitochondrial dysfunction is closely associated with a wide range of diseases, including neurodegenerative disorders (such as Alzheimer’s disease and Parkinson’s disease), cardiovascular diseases, diabetes, cancer, and aging-related pathological processes. Therefore, targeting mitochondria to enhance their function or mitigate their damage has become an important strategy in drug discovery and development.
TargetMol’s Mitochondrial Protection Compound Library is a specially designed collection of compounds for the screening and study of mitochondrial protection activities. This library comprises 920 compounds with confirmed or potential mitochondrial protective effects. These structurally diverse small molecules act through mechanisms such as maintaining mitochondrial membrane potential (ΔΨm), reducing oxidative stress–induced damage, improving mitochondrial biogenesis, and promoting mitophagy. The collection includes, but is not limited to, mPTP inhibitors, PGC-1α agonists, DRP1 inhibitors, PINK1/Parkin pathway activators, Nrf2 activators, and polyphenols.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5320

Mitochondrial Protection Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A collection of 920 compounds with potential or confirmed mitochondrial protective activity, suitable for high-throughput and high-content screening.
  • Detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are available for supply.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Apoptosis
Autophagy
NF-κB
Antibacterial
ROS
PPAR
mTOR
Endogenous Metabolite
PARP
PI3K
AMPK
Antioxidant
COX
Mitophagy
Reactive Oxygen Species
Akt
Nrf2
p38 MAPK
Antifungal
Cytochromes P450
HIV Protease
TNF
NO Synthase
Antibiotic
Influenza Virus
Caspase
ERK
Tyrosinase
Parasite
Interleukin
Ferroptosis
Virus Protease
Sirtuin
JNK
Wnt/beta-catenin
DNA/RNA Synthesis
Bcl-2 Family
Glucosidase
MMP
Anti-infection
STAT
Phosphatase
IL Receptor
PKC
glycosidase
SARS-CoV
Estrogen Receptor/ERR
Calcium Channel
Lipoxygenase
DNA-PK
Immunology/Inflammation related
HSV
HDAC
CDK
Cholinesterase (ChE)
TLR
GABA Receptor
Reductase
TRP/TRPV Channel
transporter
Dehydrogenase
Adrenergic Receptor
PDE
Mitochondrial Metabolism
TGF-beta/Smad
IκB/IKK
5-HT Receptor
AChR
HIF/HIF Prolyl-Hydroxylase
Estrogen/progestogen Receptor
GSK-3
HBV
Drug Metabolite
JAK
Xanthine Oxidase
Beta Amyloid
ATPase
NOS
Transferase
PKA
MAO
Topoisomerase
Antifection
Androgen Receptor
EGFR
P-gp
Potassium Channel
Monoamine Oxidase
PERK
VEGFR
Aryl Hydrocarbon Receptor
UGT
SGLT
ATM/ATR
Sodium Channel
NOD-like Receptor (NLR)
p53
Carbonic Anhydrase
Src
RAAS
Fatty Acid Synthase
IGF-1R
Antiviral
Prostaglandin Receptor
Free radical scavengers
Reverse Transcriptase
S6 Kinase
Ras
HMG-CoA Reductase
Microtubule Associated
Proteasome
Dopamine Receptor
Integrin
Glutathione Peroxidase
Tyrosine Kinases
Pim
Amylase
Gamma-secretase
Angiotensin-converting Enzyme (ACE)
PTEN
CaMK
MAPK
Phospholipase
HIF
Complement System
Cannabinoid Receptor
FLT
GPCR
Chloride channel
CD38
Histone Methyltransferase
ADC Cytotoxin
Adenosine Receptor
NADPH
Histamine Receptor
Necroptosis
c-Myc
Serine/threonin kinase
Glucokinase
NR4A
RANKL/RANK
Glucocorticoid Receptor
IAP
IRE1
RIP kinase
LDL
Hedgehog/Smoothened
Bombesin Receptor
PDGFR
cAMP
Epigenetic Reader Domain
Acyltransferase
Trk receptor
Histone Acetyltransferase
Casein Kinase
p62
FKBP
Retinoid Receptor
Aromatase
Hydroxylase
MEK
MDM-2/p53
Syk
c-Kit
NOD
FAK
AhR
ROS Kinase
PD-1/PD-L1
PGK1
Advanced Glycation End Products
Proton pump
NPC1L1
Monocarboxylate transporter
stilbene oxidase
HCV Protease
Dynamin
MyD88
YAP
Arginase
c-Met/HGFR
IFNAR
Arrestin
BACE
DYRK
Cell wall
Histone Demethylase
Lipase
OCT
CaSR
Serine Protease
ATG
Serotonin Transporter
Cell Cycle Arrest
Cysteine Protease
Liver X Receptor
FXR
iGluR
Annexin A
E1/E2/E3 Enzyme
Bcr-Abl
MTH1
FABP
P2X Receptor
NMDAR
ABC Transporter
Monoamine Transporter
Opioid Receptor
DPP-4
PAK
FAAH
CXCR
HCAR
Chk
Epoxide Hydrolase
Cadherin
Aurora Kinase
GluR
Thrombopoietin Receptor
Norepinephrine
DNA
Telomerase
ATP Citrate Lyase
Lipid
Beta-Secretase
PGE Synthase
PSMA
OAT
HSP
STING
LRRK2
Urea Transporter
Decarboxylase
GluCls
Pyroptosis
RSV
MELK
GST
Acetyl-CoA Carboxylase
c-Fms
Protease
PDK
FOXO
PLK
Adenosine Deaminase
CGRP Receptor
ATTECs
Platelet aggregation
NADPH-oxidase
IRAK
MLK
PGC-1α

Keywords