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TargetMol | Compound Library

Mitochondrial Protection Compound Library

Catalog No. L5320

Mitochondria play a central role in maintaining cellular energy metabolism, regulating redox homeostasis, and participating in key biological processes such as apoptosis and calcium signaling. Mitochondrial dysfunction is closely associated with a wide range of diseases, including neurodegenerative disorders (such as Alzheimer’s disease and Parkinson’s disease), cardiovascular diseases, diabetes, cancer, and aging-related pathological processes. Therefore, targeting mitochondria to enhance their function or mitigate their damage has become an important strategy in drug discovery and development.
TargetMol’s Mitochondrial Protection Compound Library is a specially designed collection of compounds for the screening and study of mitochondrial protection activities. This library comprises 920 compounds with confirmed or potential mitochondrial protective effects. These structurally diverse small molecules act through mechanisms such as maintaining mitochondrial membrane potential (ΔΨm), reducing oxidative stress–induced damage, improving mitochondrial biogenesis, and promoting mitophagy. The collection includes, but is not limited to, mPTP inhibitors, PGC-1α agonists, DRP1 inhibitors, PINK1/Parkin pathway activators, Nrf2 activators, and polyphenols.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5320

Mitochondrial Protection Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A collection of 920 compounds with potential or confirmed mitochondrial protective activity, suitable for high-throughput and high-content screening.
  • Detailed compound information with structure, target, activity, IC50 value, and brief introduction;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;
  • All compounds are available for supply.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
NF-κB
Antibacterial
mTOR
PPAR
ROS
Endogenous Metabolite
PARP
PI3K
AMPK
Antioxidant
COX
Mitophagy
Reactive Oxygen Species
Akt
Nrf2
p38 MAPK
Antifungal
Cytochromes P450
HIV Protease
TNF
NO Synthase
Antibiotic
ERK
Influenza Virus
Tyrosinase
Caspase
Interleukin
Parasite
JNK
Ferroptosis
Virus Protease
Sirtuin
Glucosidase
Bcl-2 Family
DNA/RNA Synthesis
Wnt/beta-catenin
MMP
Anti-infection
STAT
Phosphatase
IL Receptor
SARS-CoV
PKC
glycosidase
Estrogen Receptor/ERR
Calcium Channel
Lipoxygenase
Cholinesterase (ChE)
DNA-PK
GABA Receptor
Immunology/Inflammation related
HSV
HDAC
CDK
TLR
Reductase
TRP/TRPV Channel
TGF-beta/Smad
IκB/IKK
AChR
PDE
Xanthine Oxidase
Antifection
Dehydrogenase
Adrenergic Receptor
transporter
5-HT Receptor
Mitochondrial Metabolism
HIF/HIF Prolyl-Hydroxylase
GSK-3
JAK
Estrogen/progestogen Receptor
Drug Metabolite
Beta Amyloid
HBV
PKA
MAO
EGFR
NOS
Topoisomerase
P-gp
Androgen Receptor
Transferase
Monoamine Oxidase
Potassium Channel
ATPase
ATM/ATR
Sodium Channel
Aryl Hydrocarbon Receptor
p53
UGT
SGLT
NOD-like Receptor (NLR)
VEGFR
RAAS
Reverse Transcriptase
Prostaglandin Receptor
Free radical scavengers
Fatty Acid Synthase
HMG-CoA Reductase
Microtubule Associated
Antiviral
S6 Kinase
Angiotensin-converting Enzyme (ACE)
Ras
Carbonic Anhydrase
Src
PERK
IGF-1R
Proteasome
Integrin
Phospholipase
HIF
Glutathione Peroxidase
Amylase
PTEN
Cannabinoid Receptor
Dopamine Receptor
Pim
CaMK
FLT
Gamma-secretase
MAPK
Complement System
Tyrosine Kinases
Histamine Receptor
Hedgehog/Smoothened
Epigenetic Reader Domain
Acyltransferase
GPCR
Adenosine Receptor
c-Myc
cAMP
Histone Acetyltransferase
Aromatase
MDM-2/p53
Platelet aggregation
NOD
ROS Kinase
PD-1/PD-L1
Chloride channel
Serine/threonin kinase
IRE1
LDL
FKBP
Retinoid Receptor
Histone Methyltransferase
RIP kinase
FAK
ADC Cytotoxin
NADPH
Necroptosis
RANKL/RANK
Glucocorticoid Receptor
Bombesin Receptor
MEK
c-Kit
AhR
Glucokinase
Trk receptor
Syk
CD38
NR4A
IAP
PDGFR
Casein Kinase
p62
Hydroxylase
PGK1
NPC1L1
Serotonin Transporter
Beta-Secretase
HSP
Decarboxylase
FOXO
Adenosine Deaminase
Arginase
c-Met/HGFR
DYRK
CaSR
Liver X Receptor
PAK
MELK
GST
IRAK
Proton pump
Monocarboxylate transporter
HCV Protease
MyD88
Arrestin
Cysteine Protease
FXR
FABP
Opioid Receptor
CXCR
Epoxide Hydrolase
Cadherin
Norepinephrine
STING
LRRK2
GluCls
Pyroptosis
Acetyl-CoA Carboxylase
CGRP Receptor
NADPH-oxidase
MLK
Bcr-Abl
P2X Receptor
Aurora Kinase
Thrombopoietin Receptor
PGE Synthase
Urea Transporter
Advanced Glycation End Products
YAP
IFNAR
BACE
Cell wall
OCT
Annexin A
Telomerase
Lipid
PSMA
PDK
Dynamin
Lipase
Serine Protease
Cell Cycle Arrest
MTH1
NMDAR
DPP-4
HCAR
Chk
OAT
RSV
c-Fms
Protease
PLK
stilbene oxidase
Histone Demethylase
ATG
iGluR
E1/E2/E3 Enzyme
ABC Transporter
Monoamine Transporter
FAAH
GluR
DNA
ATP Citrate Lyase
PGC-1α

Keywords