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Raludotatug deruxtecan

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Catalog No. T77474
Alias R-DXd, MK-5909, MK5909, DS-6000a, DS-6000

Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.

Raludotatug deruxtecan

Raludotatug deruxtecan

😃Good
Catalog No. T77474Alias R-DXd, MK-5909, MK5909, DS-6000a, DS-6000
Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$447InquiryInquiry
5 mg$1,400InquiryInquiry
10 mg$2,240InquiryInquiry
25 mg$4,210InquiryInquiry
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:>95.0% (SDS-PAGE); 98.4% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.
In vitro
Raludotatug deruxtecan is an antibody-drug conjugate (ADC) targeting CDH6. Raludotatug deruxtecan showed in vitro cell growth inhibition activity in high CDH6 tumor cells, but not in low CDH6 tumor cells. [1]
In vivo
The high cell line of CDH6 in a mouse xenograft model showed strong antitumor activity and tumor regression. Raludotatug deruxtecan showed high efficacy in PDX models. [1]
SynonymsR-DXd, MK-5909, MK5909, DS-6000a, DS-6000
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
DXd
Antigen Details
Gene ID
Uniprot ID
TargetCDH6/K-Cadherin
Chemical Properties
Molecular Weight145.54 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG1 kappa-DXd
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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