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Raludotatug deruxtecan
(Synonyms: R-DXd, MK-5909, MK5909, DS-6000a, DS-6000) Copy Product Info
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Synonyms: R-DXd, MK-5909, MK5909, DS-6000a, DS-6000
Catalog No. T77474 Copy Product Info
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Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.
Raludotatug deruxtecan
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $500 | 6-8 weeks | 6-8 weeks | |
| 5 mg | $1,350 | 6-8 weeks | 6-8 weeks | |
| 10 mg | $2,240 | 6-8 weeks | 6-8 weeks | |
| 25 mg | Inquiry | 6-8 weeks | 6-8 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer. |
| In vitro | Raludotatug deruxtecan is an antibody-drug conjugate (ADC) targeting CDH6. Raludotatug deruxtecan showed in vitro cell growth inhibition activity in high CDH6 tumor cells, but not in low CDH6 tumor cells. [1] |
| In vivo | The high cell line of CDH6 in a mouse xenograft model showed strong antitumor activity and tumor regression. Raludotatug deruxtecan showed high efficacy in PDX models. [1] |
| Synonyms | R-DXd, MK-5909, MK5909, DS-6000a, DS-6000 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | DXd |
| Gene ID | |
| Uniprot ID | |
| Target | CDH6/K-Cadherin |
| Molecular Weight | 145.54 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa-DXd |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Raludotatug deruxtecan in vivo | Raludotatug deruxtecan in vitro | Raludotatug deruxtecan molecular weight
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