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Raludotatug deruxtecan (Synonyms: R-DXd, MK-5909, MK5909, DS-6000a, DS-6000)

Catalog No. T77474 Copy Product Info
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Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.

Raludotatug deruxtecan

Copy Product Info
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Catalog No. T77474
Synonyms R-DXd, MK-5909, MK5909, DS-6000a, DS-6000

Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.

Raludotatug deruxtecan
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$5006-8 weeks6-8 weeks
5 mg$1,3506-8 weeks6-8 weeks
10 mg$2,2406-8 weeks6-8 weeks
25 mgInquiry6-8 weeks6-8 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Raludotatug deruxtecan (DS-6000) is an ADC compound targeting CDH6 with anti-cancer activity, used in the study of ovarian cancer.
In vitro
Raludotatug deruxtecan is an antibody-drug conjugate (ADC) targeting CDH6. Raludotatug deruxtecan showed in vitro cell growth inhibition activity in high CDH6 tumor cells, but not in low CDH6 tumor cells. [1]
In vivo
The high cell line of CDH6 in a mouse xenograft model showed strong antitumor activity and tumor regression. Raludotatug deruxtecan showed high efficacy in PDX models. [1]
SynonymsR-DXd, MK-5909, MK5909, DS-6000a, DS-6000
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
DXd
Antigen Details
Gene ID
Uniprot ID
TargetCDH6/K-Cadherin
Chemical Properties
Molecular Weight145.54 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG1 kappa-DXd
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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