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Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3)
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Catalog No. T9901A-189
Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) is a rat-derived agonistic antibody targeting mouse 4-1BB/CD137 that can stimulate 4-1BB signaling and induce T cell-mediated anti-tumor immunity. Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) can be used in research on cancer, infection, immunology, and neurological diseases, such as glioblastoma and retroviral infection .
Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3)
Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3)
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Purity: 95%
Catalog No. T9901A-189
Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) is a rat-derived agonistic antibody targeting mouse 4-1BB/CD137 that can stimulate 4-1BB signaling and induce T cell-mediated anti-tumor immunity. Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) can be used in research on cancer, infection, immunology, and neurological diseases, such as glioblastoma and retroviral infection .
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $245 | 4-6 weeks | 4-6 weeks | |
| 5 mg | $535 | 4-6 weeks | 4-6 weeks | |
| 10 mg | Preferential | 4-6 weeks | 4-6 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
Appearance:Liquid
Color:Transparent
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| Description | Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) is a rat-derived agonistic antibody targeting mouse 4-1BB/CD137 that can stimulate 4-1BB signaling and induce T cell-mediated anti-tumor immunity. Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) can be used in research on cancer, infection, immunology, and neurological diseases, such as glioblastoma and retroviral infection . |
| In vivo | Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) in combination with anti-PD-1 (200 μg, intraperitoneal injection, every 3 days starting from day 9) can improve the function of tumor-infiltrating lymphocytes in glioblastoma models and prolong the survival of CT2A tumor-bearing mice [1].
Anti-Mouse 4-1BB/CD137 Antibody (LOB12.3) (100 μg, intraperitoneal injection, every other day starting from day 4 post-infection) can slightly increase the number of virus-specific CD4+ T cells and significantly enhance the expression level of granzyme B (GzmB) in mice infected with Friend retrovirus [2]. |
| Clone | LOB12.3 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | 4-1BB/CD137 |
| Isotype | Rat IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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