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PROTAC Androgen receptor degrader-1
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Catalog No. T212553Cas No. 3056515-10-4
PROTAC Androgen receptor degrader-1 (Ex. 14) is a PROTAC degrader targeting the androgen receptor (DC50 = 6 nM), which can be used for the study of prostate cancer.
PROTAC Androgen receptor degrader-1
😃Good
Purity: 99.49%
Catalog No. T212553Cas No. 3056515-10-4
PROTAC Androgen receptor degrader-1 (Ex. 14) is a PROTAC degrader targeting the androgen receptor (DC50 = 6 nM), which can be used for the study of prostate cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $419 | - | In Stock | |
| 5 mg | $963 | - | In Stock | |
| 10 mg | $1,290 | - | In Stock | |
| 25 mg | $1,920 | - | In Stock | |
| 50 mg | $2,580 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.49%
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | PROTAC Androgen receptor degrader-1 (Ex. 14) is a PROTAC degrader targeting the androgen receptor (DC50 = 6 nM), which can be used for the study of prostate cancer. |
| Targets&IC50 | Androgen receptor:6 nM (DC50) |
| Molecular Weight | 758.35 |
| Formula | C43H48ClN9O2 |
| Cas No. | 3056515-10-4 |
| Smiles | C(#N)C=1C=2C(=C(C=CC2Cl)N3C[C@@H](CCC3)C4=CC=C(C=C4)N5CCC(CN6CCC(CC6)C=7N(C)C=8C(C7)=CC=C(C8)N9C(=O)NC(=O)CC9)CC5)NN1 |
| Color | Pink |
| Appearance | Solid |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSO (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyThe above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
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