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SB-215505 is a subtype-selective 5-HT2B receptor antagonist that inhibits 5-HT2B, 5-HT2A, and 5-HT2C.SB-215505 can be used to study prostate cancer.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $146 | In Stock | |
| 5 mg | $363 | In Stock | |
| 10 mg | $497 | In Stock | |
| 25 mg | $816 | In Stock | |
| 50 mg | $1,130 | In Stock | |
| 100 mg | $1,530 | In Stock | |
| 200 mg | $1,980 | In Stock |
| Description | SB-215505 is a subtype-selective 5-HT2B receptor antagonist that inhibits 5-HT2B, 5-HT2A, and 5-HT2C.SB-215505 can be used to study prostate cancer. |
| Targets&IC50 | 5-HT2A Receptor:6.77 (pKi), 5-HT2C Receptor:7.66 (pKi), 5-HT2B Receptor:8.3 (pKi) |
| In vivo | In male Sprague-Dawley rats weighing 230-260 g, SB-215505 (0.1, 0.3, and 1.0 mg/kg; intraperitoneal injection; two doses) dose-dependently increased wakefulness (W) and decreased intermediate stage of sleep (IS), paradoxical sleep (PS), and slow-wave sleep stage 2 (SWS-2)[2]. |
| Synonyms | SB215505, SB 215505 |
| Molecular Weight | 337.8 |
| Formula | C19H16ClN3O |
| Cas No. | 162100-15-4 |
| Smiles | Cc1cc2CCN(C(=O)Nc3cccc4ncccc34)c2cc1Cl |
| Relative Density. | 1.385 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |

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