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3-Methoxy-9H-Carbazole

Name: 3-Methoxy-9H-Carbazole
Brand: TargetMol
SKU: T77681
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77681Cas No. 18992-85-3

3-methoxy-9H-carbazole is a photosensitizer, a natural compound from Klauseneria heptaphylla and Klauseneria indica.3-methoxy-9H-carbazole has anti-breast cancer activity and induces apoptosis.

3-Methoxy-9H-Carbazole

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Purity: 99.24%

Catalog No. T77681Cas No. 18992-85-3

3-methoxy-9H-carbazole is a photosensitizer, a natural compound from Klauseneria heptaphylla and Klauseneria indica.3-methoxy-9H-carbazole has anti-breast cancer activity and induces apoptosis.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$35	-	In Stock
50 mg	$56	-	In Stock
100 mg	$89	-	In Stock
500 mg	$228	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.24%

Appearance:Solid

Color:Purple

Resource Download

COA HNMR LCMS

Product Introduction

3-Methoxy-9H-Carbazole AI Summary

3-Methoxy-9H-Carbazole exhibits a range of bioactivities, including potential as an inhibitor and activator in various biological assays. Specifically, it has been studied for its inhibition of human C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity, demonstrating 15.0% inhibition at 20 uM after 30 minutes by a luciferase-derived luminescence assay. Additionally, this compound shows potency in inhibiting enzymes such as HSD17B4, ALDH1A1, HPGD, and HCV. It also demonstrates inhibitory effects on tau fibril formation and influenza NS1 protein function and shows potential as an activator of ClpP and as an inducer of the Endoplasmic Reticulum Stress Response in human glioma cells..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

3-methoxy-9H-carbazole is a photosensitizer, a natural compound from Klauseneria heptaphylla and Klauseneria indica.3-methoxy-9H-carbazole has anti-breast cancer activity and induces apoptosis.

Chemical Properties

Molecular Weight	197.23
Formula	C₁₃H₁₁NO
Cas No.	18992-85-3
Smiles	COc1ccc2[nH]c3ccccc3c2c1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (278.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.0702 mL	25.3511 mL	50.7022 mL	253.5111 mL
5 mM	1.0140 mL	5.0702 mL	10.1404 mL	50.7022 mL
10 mM	0.5070 mL	2.5351 mL	5.0702 mL	25.3511 mL
20 mM	0.2535 mL	1.2676 mL	2.5351 mL	12.6756 mL
50 mM	0.1014 mL	0.5070 mL	1.0140 mL	5.0702 mL
100 mM	0.0507 mL	0.2535 mL	0.5070 mL	2.5351 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc