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Anti-Mouse CTLA-4 Antibody (9H10) is a Syrian hamster inhibitory antibody that targets CTLA-4.Anti-Mouse CTLA-4 Antibody (9H10) binds to mouse CTLA-4 and blocks the interaction between CTLA-4 and its ligands, showing significant antitumor effects in various tumor models such as breast cancer and colon cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $76 | 4-6 weeks | 4-6 weeks | |
| 5 mg | $278 | 4-6 weeks | 4-6 weeks | |
| 10 mg | Preferential | 4-6 weeks | 4-6 weeks |
| Description | Anti-Mouse CTLA-4 Antibody (9H10) is a Syrian hamster inhibitory antibody that targets CTLA-4.Anti-Mouse CTLA-4 Antibody (9H10) binds to mouse CTLA-4 and blocks the interaction between CTLA-4 and its ligands, showing significant antitumor effects in various tumor models such as breast cancer and colon cancer. |
| In vivo | Anti-Mouse CTLA-4 Antibody (9H10) (200 μg, i.p., on days 15, 18, and 21) combined with radiotherapy inhibits tumor growth and metastasis in 4T1 tumor-bearing mice [1]. Anti-Mouse CTLA-4 Antibody (9H10) (200 μg, i.p., on days 1, 4, and 7) combined with radiotherapy suppresses tumor growth and prolongs survival in 4T1 tumor-bearing mice [2]. Anti-Mouse CTLA-4 Antibody (9H10) (200 μg, i.p., on days 14, 17, and 20) combined with radiotherapy inhibits the growth of primary and secondary tumors in mouse models of breast cancer and colon cancer [3]. Anti-Mouse CTLA-4 Antibody (9H10) (100 μg initial dose, followed by 50 μg every 3 days for two doses, i.p.) improves the long-term survival rate of mice with astroglioma models without inducing experimental autoimmune encephalomyelitis [4]. |
| Clone | 9H10 |
| Reactivity | Mouse |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CTLA-4/CD152 |
| Molecular Weight | 150 kDa |
| Isotype | Syrian hamster IgG |
| Recommended Isotype Control |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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