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HDAC6/HSP90-IN-3

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Catalog No. T212505

HDAC6/HSP90-IN-3 is an orally active dual inhibitor of histone deacetylase 6 (HDAC6) and heat shock protein 90 (HSP90), with IC50 values of 28 nM and 0.88 μM, respectively. This compound shows potential for use in research on malignant tumors such as prostate cancer.

HDAC6/HSP90-IN-3

HDAC6/HSP90-IN-3

😃Good
Catalog No. T212505
HDAC6/HSP90-IN-3 is an orally active dual inhibitor of histone deacetylase 6 (HDAC6) and heat shock protein 90 (HSP90), with IC50 values of 28 nM and 0.88 μM, respectively. This compound shows potential for use in research on malignant tumors such as prostate cancer.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
HDAC6/HSP90-IN-3 is an orally active dual inhibitor of histone deacetylase 6 (HDAC6) and heat shock protein 90 (HSP90), with IC50 values of 28 nM and 0.88 μM, respectively. This compound shows potential for use in research on malignant tumors such as prostate cancer.
Targets&IC50
HDAC6:28 nM
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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