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Labetuzumab govitecan (Synonyms: Labetuzumab-SN38, IMMU-130, IMMU130, IMMU 130, hMN14-SN38, hMN-14-SN-38)
Catalog No. T25593 Copy Product Info
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Labetuzumab govitecan is an antibody-drug conjugate (ADC) targeting CEACAM5, composed of the labetuzumab antibody, the payload SN-38, and a pH-sensitive linker. It can be used in research on malignant tumors such as colorectal cancer.
Labetuzumab govitecan
Copy Product Info🥰Excellent
Catalog No. T25593
Synonyms Labetuzumab-SN38, IMMU-130, IMMU130, IMMU 130, hMN14-SN38, hMN-14-SN-38
Labetuzumab govitecan is an antibody-drug conjugate (ADC) targeting CEACAM5, composed of the labetuzumab antibody, the payload SN-38, and a pH-sensitive linker. It can be used in research on malignant tumors such as colorectal cancer.
Cas No. 1469876-18-3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $622 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $1,620 | 2-4 weeks | 2-4 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Labetuzumab govitecan is an antibody-drug conjugate (ADC) targeting CEACAM5, composed of the labetuzumab antibody, the payload SN-38, and a pH-sensitive linker. It can be used in research on malignant tumors such as colorectal cancer. |
| In vivo | Labetuzumab govitecan administered intraperitoneally at a total dose of 1.0 mg prolongs the median survival in a mouse model of GW-39 lung metastasis. Labetuzumab govitecan administered intraperitoneally at 25 mg/kg twice weekly for 4 weeks prolongs the median survival in a LS174T subcutaneous xenograft nude mouse model [2]. |
| Synonyms | Labetuzumab-SN38, IMMU-130, IMMU130, IMMU 130, hMN14-SN38, hMN-14-SN-38 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal, ADC |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | SN38 |
| Gene ID | |
| Uniprot ID | |
| Target | CEACAM5/CEA/CD66e |
| Cas No. | 1469876-18-3 |
| Relative Density. | no data available |
| Isotype | IgG1 |
| Storage | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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