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BQ7859

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Catalog No. T203144

BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).

BQ7859

BQ7859

😃Good
Catalog No. T203144
BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).
Chemical Properties
Molecular Weight1276.43
FormulaC62H89N11O18
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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